{"id":3319,"date":"2026-07-25T11:59:19","date_gmt":"2026-07-25T09:59:19","guid":{"rendered":"https:\/\/www.drcolle.be\/dienst\/biofiller-autologous-gel-from-your-own-blood\/"},"modified":"2026-07-26T20:20:31","modified_gmt":"2026-07-26T18:20:31","slug":"biofiller-autologous-gel-from-your-own-blood","status":"publish","type":"dienst","link":"https:\/\/www.drcolle.be\/en\/dienst\/biofiller-autologous-gel-from-your-own-blood\/","title":{"rendered":"Biofiller: autologous gel from your own blood"},"content":{"rendered":"\n<div class=\"wp-block-columns alignfull are-vertically-aligned-top is-layout-flex wp-container-core-columns-is-layout-b81f3336 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-cover has-custom-content-position is-position-bottom-center\" style=\"padding-top:var(--wp--preset--spacing--128-65);padding-bottom:var(--wp--preset--spacing--64-32);min-height:560px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1707\" class=\"wp-block-cover__image-background wp-image-4238 size-full\" alt=\"Close-up van hals en decollet\u00e9 \u2014 biofiller bij dr. Julien Colle\" src=\"https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete.png\" data-object-fit=\"cover\" srcset=\"https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete.png 2560w, https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete-300x200.png 300w, https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete-1024x683.png 1024w, https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete-768x512.png 768w, https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete-1536x1024.png 1536w, https:\/\/www.drcolle.be\/wp-content\/uploads\/2026\/07\/huidverjonging-hals-en-decollete-2048x1366.png 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-100 has-background-dim wp-block-cover__gradient-background has-background-gradient has-header-overlay-gradient-background\"><\/span><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-block-cover-is-layout-constrained\">\n\n<div class=\"wp-block-group alignwide has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-e896cbe3 wp-block-group-is-layout-constrained\">\n\n<h1 class=\"wp-block-heading\">Biofiller: autologous gel from your own blood<\/h1>\n\n\n<p class=\"is-style-default wp-block-paragraph\">A biofiller is a gel prepared from your own blood. It provides a soft volumizing effect while simultaneously stimulating tissue repair, without the introduction of any foreign substances. <\/p>\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\" style=\"margin-top:var(--wp--preset--spacing--24-16)\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/agenda.mediris.be\/appointments?agenda=5a9f0a87-cb2f-460c-9e5d-f2eb27b69c94&amp;careprovider=e46d1dc1-89af-430c-b647-9b95d15ad5ba\" target=\"_blank\" rel=\"noopener\">Make an appointment<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<h2 id=\"wat-is-een-biofiller\" class=\"wp-block-heading\">What is a biofiller?<\/h2>\n\n<p class=\"wp-block-paragraph\">In a biofiller procedure, an albumin gel is prepared from your own plasma through controlled heating. This gel is then mixed with your own platelet concentrate. The result is a completely autologous gel with two simultaneous properties: a soft, discrete volumizing effect and a biostimulating effect due to the sustained release of growth factors.  <\/p>\n\n<p class=\"wp-block-paragraph\">The preparation takes place entirely in the practice on the day of treatment. Nothing is added that does not come from your own blood. <\/p>\n\n<h2 id=\"hoe-werkt-het\" class=\"wp-block-heading\">How does it work?<\/h2>\n\n<p class=\"wp-block-paragraph\">Albumin is a protein that occurs naturally in blood plasma. By heating the plasma in a controlled manner, the structure of this protein changes, creating a viscous gel. This gel acts as a carrier: it slowly releases the mixed growth factors into the surrounding tissue.  <\/p>\n\n<p class=\"wp-block-paragraph\">As a result, a biofiller works on two levels. In the short term, the gel provides a light filling effect. In the longer term, skin quality, elasticity, and hydration improve because the growth factors stimulate fibroblasts to produce new collagen.  <\/p>\n\n<p class=\"wp-block-paragraph\">The duration of action of the gel itself is typically about four to six months. The biostimulating effect lasts longer. <\/p>\n\n<h2 id=\"voor-wie-is-deze-behandeling-geschikt\" class=\"wp-block-heading\">Who is this treatment suitable for?<\/h2>\n\n<p class=\"wp-block-paragraph\">Treated areas include:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>the tear trough and dark circles<\/li>\n\n\n\n<li>fine lines<\/li>\n\n\n\n<li>the midface and the temple<\/li>\n\n\n\n<li>the nasolabial fold and marionette lines<\/li>\n\n\n\n<li>the jawline<\/li>\n<\/ul>\n\n<p class=\"wp-block-paragraph\">The biofiller is particularly suitable for those who desire a discrete correction and consciously wish to avoid foreign materials. Those seeking a pronounced increase in volume or a sharply defined contour are better suited for a <a href=\"https:\/\/www.drcolle.be\/en\/dienst\/hyaluronic-acid-fillers\/\">hyaluronic acid filler<\/a>. <\/p>\n\n<h2 id=\"hoe-verloopt-een-sessie\" class=\"wp-block-heading\">What happens during a session?<\/h2>\n\n<p class=\"wp-block-paragraph\">The skin is cleansed and the treatment areas are marked. Blood is drawn, after which the plasma and platelet concentrate are prepared. This preparation takes time, meaning a session typically lasts about an hour to an hour and fifteen minutes.  <\/p>\n\n<p class=\"wp-block-paragraph\">The gel is then injected at the correct depth using a needle or a blunt cannula. Because the gel is thicker than a liquid concentrate, a classic technique is used. <\/p>\n\n<p class=\"wp-block-paragraph\">Afterwards, swelling and sometimes bruising are normal, particularly around the eyes. These usually disappear within a few days. <\/p>\n\n<h2 id=\"aantal-sessies-en-resultaat\" class=\"wp-block-heading\">Number of sessions and results<\/h2>\n\n<p class=\"wp-block-paragraph\">Typically, two to three sessions are planned, with four to eight weeks in between. The result is assessed after six to twelve weeks, after which maintenance once or twice a year is common. <\/p>\n\n<p class=\"wp-block-paragraph\">The result varies from person to person. There is an obligation of means and not an obligation of result. <\/p>\n\n<h2 id=\"wat-deze-behandeling-niet-doet\" class=\"wp-block-heading\">What this treatment does not do<\/h2>\n\n<ul class=\"wp-block-list\">\n<li>A biofiller is <strong>not a classic volumizer<\/strong>. It provides a soft correction, not a pronounced projection of the cheekbone or chin. <\/li>\n\n\n\n<li>It does not tighten sagging skin and is not a substitute for a facelift, neck lift, or eyelid surgery.<\/li>\n\n\n\n<li><strong>Important difference from hyaluronic acid:<\/strong> a biofiller cannot be dissolved with hyaluronidase. Therefore, a subsequent correction is not possible in the same way. For this reason, dosing is performed conservatively.  <\/li>\n\n\n\n<li>The effect is temporary and requires maintenance.<\/li>\n<\/ul>\n\n<h2 id=\"veiligheid-en-contra-indicaties\" class=\"wp-block-heading\">Safety and contraindications<\/h2>\n\n<p class=\"wp-block-paragraph\">The treatment is not performed during pregnancy or breastfeeding, in the presence of an active infection in the treatment area, coagulation disorders, a very low platelet count or other blood abnormalities, active autoimmune disease, or cancer under active treatment.<\/p>\n\n<p class=\"wp-block-paragraph\">Because it involves autologous material, there is no risk of rejection or allergy to the product itself. The usual risks of an injection still apply: swelling, bruising, sensitivity and, rarely, a vascular complication. Therefore, the treatment is performed exclusively by the physician.  <\/p>\n\n<h2 id=\"nazorg\" class=\"wp-block-heading\">Aftercare<\/h2>\n\n<ul class=\"wp-block-list\">\n<li>Do not massage the treated area for the first few days.<\/li>\n\n\n\n<li>No makeup for twenty-four hours.<\/li>\n\n\n\n<li>No sauna, steam bath, or intensive exercise for forty-eight hours.<\/li>\n\n\n\n<li>Sleep with your head slightly elevated for the first few nights to limit swelling.<\/li>\n\n\n\n<li>Please contact us in case of increasing pain or skin discoloration.<\/li>\n<\/ul>\n\n<h2 id=\"combinatie-met-chirurgie-en-andere-behandelingen\" class=\"wp-block-heading\">Combination with surgery and other treatments<\/h2>\n\n<p class=\"wp-block-paragraph\">A biofiller is often combined with a <a href=\"https:\/\/www.drcolle.be\/en\/dienst\/facial-prp-treatment\/\">PRP facial treatment<\/a> or with <a href=\"https:\/\/www.drcolle.be\/en\/dienst\/rf-microneedling-skin-tightening-without-surgery\/\">RF microneedling<\/a>, which work on skin quality while the gel softens the contour. In cases of significant volume loss, <a href=\"https:\/\/www.drcolle.be\/en\/dienst\/facial-lipofilling\/\">facial lipofilling<\/a> is a more permanent alternative. In cases of sagging, a <a href=\"https:\/\/www.drcolle.be\/en\/dienst\/facelift\/\">facelift<\/a> will be discussed.  <\/p>\n\n<h2 id=\"veelgestelde-vragen\" class=\"wp-block-heading\">Frequently asked questions<\/h2>\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>What is the difference compared to a regular filler?<\/summary>\n<p class=\"wp-block-paragraph\">A classic filler consists of cross-linked hyaluronic acid, a foreign product that provides volume and can be dissolved with an enzyme. A biofiller comes entirely from your own blood, provides a softer correction, and additionally stimulates tissue repair. <\/p>\n<\/details>\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Can a biofiller be dissolved?<\/summary>\n<p class=\"wp-block-paragraph\">No. Unlike hyaluronic acid, a biofiller cannot be dissolved with hyaluronidase. Therefore, dosing is deliberately conservative and performed in stages.  <\/p>\n<\/details>\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>How long does the effect last?<\/summary>\n<p class=\"wp-block-paragraph\">The gel itself typically works for about four to six months. The biostimulating effect on skin quality lasts longer. Maintenance is usually scheduled once or twice a year.  <\/p>\n<\/details>\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>How many sessions are needed?<\/summary>\n<p class=\"wp-block-paragraph\">Typically two to three sessions with four to eight weeks in between. The result is assessed after six to twelve weeks. <\/p>\n<\/details>\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Can a biofiller be used in the tear trough?<\/summary>\n<p class=\"wp-block-paragraph\">Yes, that is one of the most requested applications. Limited quantities are used because the skin there is very thin. Bruising is more common in this area.  <\/p>\n<\/details>\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Is the treatment painful?<\/summary>\n<p class=\"wp-block-paragraph\">The blood draw feels like a standard blood test. A numbing cream or local anesthetic is used for the injection of the gel, making it generally well-tolerated. <\/p>\n<\/details>\n\n<h2 id=\"lees-ook\" class=\"wp-block-heading\">Read also<\/h2>\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.drcolle.be\/en\/dienst\/wrinkle-treatment\/\">Wrinkle treatment<\/a><\/li>\n<\/ul>\n\n<div class=\"wp-block-group medische-disclaimer has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-top-style:solid;border-top-width:1px;margin-top:var(--wp--preset--spacing--48-32);padding-top:var(--wp--preset--spacing--24-16)\">\n<p class=\"has-link-color has-small-font-size wp-elements-7496b57ae5c3750201a4e0182fa89cd5 wp-block-paragraph\"><\/p><p class=\"has-small-font-size\" style=\"opacity:.7\">This text is general in nature and does not replace personal medical advice. An obligation of means applies, not an obligation of results. What is possible in your situation is determined during a consultation and recorded in writing. Read the full <a href=\"https:\/\/www.drcolle.be\/en\/medical-disclaimer\/\">medical disclaimer<\/a>.   <\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>What is a biofiller? In a biofiller procedure, an albumin gel is prepared from your own plasma through controlled heating. This gel is then mixed with your own platelet concentrate. The result is a completely autologous gel with two simultaneous properties: a soft, discrete volumizing effect and a biostimulating effect due to the sustained release [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","rank_math_title":"Biofiller: 3 steps and recovery | dr. Colle, specialist","rank_math_description":"A biofiller is a gel from your own blood that supports volume and skin quality. Read how the treatment proceeds and what you can realistically expect. 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